Primary cutaneous peripheral T cell lymphoma not otherwise specified (PTL-NOS): an aggressive cutaneous lymphoma
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Abstract Background: Background: Peripheral T cell lymphoma not otherwise specified (PTL-NOS) is the rare subset of peripheral T cell lymphoma, which is a heterogeneous group of Non-Hodgkin lymphoma. It often presents with rare dermatological manifestations and fatal outcomes. Case Presentation: A 35 years old male with no known comorbidity presented with 4 months history of progressively growing multiple small to medium sized nodules and plaques on face, shoulder, chest, back, and abdomen. Plaques were smooth, erythematous with erosion and ulceration present over some of the lesions. Histopathology shows dense lymphoid infiltrate involving epidermis as well as up to deep dermis. Immunohistochemistry and histopathology findings favoured the diagnosis of Peripheral T-cell Lymphoma Not Otherwise Specified. CT scan of brain, chest and abdomen excluded visceral involvement. Conclusion: This is a rare subgroup of peripheral T cell lymphoma often confused with other cutaneous T cell lymphoma like Mycosis Fungoides. But this is more aggressive and often needs standard combination chemotherapy upon diagnosis. Keywords: PTCL-NOS, Primary Cutaneous Peripheral T cell Lymphoma Not Otherwise Specified |